How To Collect And Preserve Tissue Samples

In general keeping and preserving biological samples for research and genetic manipulation usually requires a collection of ultra-low-temperature devices for storing and processing slowly biochemical processes within tissues and blood specimens. This is the ultimate objective for the collection of DNA samples and preservation is vital to understand the diversity of a specimen.

While biological specimens are often taken for molecular research or clinical study. The preservation process at biorepository can also be used to better understand biospecimen research. The preservation of animal skin or fluid for long-term storage needs specialized sampling, statistical analysis, and examination methods.


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General Rules:

The biological materials have to be stored at a particular temperature for an extended period of time. Typically, objects that are stored over shorter periods must be frozen for extended durations or at a temperature that is suitable for rapid use. While some shipping containers utilize dry ice to manage the temperature. 

However. insulated cold chain shipping containers often rely on the combination of phase change materials and high-grade insulation to thermally protect and transport temperature-sensitive biologic products from point of manufacture to patient. For storage that requires ultracold temperatures dry ice is commonly employed as the phase-change material since it melts at temperatures of -70C. 

Other limitations of a material that undergoes a phase change like dry ice are that the container is not airtight since sublimation of dry ice causes expanding gas and an increase in pressure. If the pressure isn't properly ventilated, airtight dry ice containers may cause an explosion of a small size.

There are several things to keep in mind for storing biospecimen samples. Some of them are mentioned below. have a look at them.

  • Drying
  • Desiccants
  • Chemical Preservation
  • Transport of biological samples